Joint pain, arthritis, muscle aches.
DOKBUASEE
Kraduk Kai Dam
scientific name: Justicia gendaruusa Burm. f.
Family name: Acanthaceae
Botanical characteristics: It is an herbaceous plant or small shrub, reaching a height of approximately 90-100 centimeters. The stem is dark red to black or purplish, smooth and glossy. The stem and branches are segmented, resembling chicken bones, with stem nodes approximately 2.5-3 inches long and branch nodes approximately 1-1.5 inches long. The stem, branches, and leaves have a reddish tint.
Important substances found in Kraduk Kai Dam
Apigenin
Research confirms: It is found abundantly in the leaves of the Kraduk Kai Dam
Effects: Anti-inflammatory
Vitexin
Research confirms: Black chicken bones have been found.
Effects: Antioxidant and anti-inflammatory.
Quercetin
Effects: Anti-inflammatory, antibacterial, and vascular protective.
Properties according to Thai traditional medicine.
The leaves help improve blood circulation, relieve coughs, headaches, vomiting blood, internal bruising, joint pain, and treat animal bites and stings.
Research benefits
A comparative study of massage with Kraduk Kai Dam oil and Zingiber oil was conducted on people experiencing neck, shoulder, and back pain, or office syndrome. Zingiber oil is known to relieve pain. The results showed that "massage with Kraduk Kai Dam oil was as effective in relieving pain as massage with Zingiber oil." Therefore, Kraduk Kai Dam oil can be used as a substitute for Zingiber oil.
1. Anti-inflammatory
Experiments in mice with swollen paws treated with apigenin from Kraduk Kai Dam showed that it could inhibit swelling by 89% at a dose of 10 milligrams per kilogram of body weight.
Furthermore, experiments with simulated human white blood cells showed that Apigenin can reduce several inflammatory mediators and increase levels of anti-inflammatory substances.
2. 2. Antioxidant activity
What is oxidation?
oxidation is a chemical process in which a substance loses electrons or reacts with oxygen, resulting in changes to its structure and properties. This process is commonly seen in sources such as pollution, factory smoke, barbecue smoke, dust, rust, and wood burning.
What is oxidation in the human body?
Oxidation occurs constantly in our bodies, such as in the creation of energy at the cellular level. Excessive oxidation leads to oxidative stress causing cell damage, accelerating bodily deterioration, and is associated with various chronic diseases such as chronic inflammation, heart disease, cancer, and neurological disorders.
In vitro research has shown that the leaves of the Kraduk Kai Dam contain the highest amount of total phenolic compounds and total flavonoids (antioxidants) compared to other extracts from the same plant leaves.
In in vivo animal studies, ethanol extracts from Kraduk Kai Dam leaves at doses of 250 and 500 mg/kg body weight were found to increase the levels of antioxidant enzymes, namely catalase and glutathione, and decrease the levels of thiobarbituric acid reactive substances (TBARS). Higher TBARS levels indicate greater cell damage from free radicals.
Therefore, the ethanol extract fromKraduk Kai Dam leaves exhibits antioxidant activity both in vitro and in vivo.
3. Relieves muscle and joint pain.
A study compared Kraduk Kai Dam spray and diclofenac spray, dividing people into two groups with mild to moderate pain. The first group used Kraduk Kai Dam spray (48 people), and the second group used diclofenac spray (47 people). The results showed no significant difference in pain levels between the two groups. Following treatment, both groups also took similar amounts of paracetamol.
In conclusion, Kraduk Kai Dam spray is comparable in efficacy to diclofenac spray with low to moderate severity.
Products made fromKraduk Kai Dam.
- Kraduk Kai Dam balm
- Kraduk Kai Dam Oil
- Kraduk Kai Dam spray
Reference
เทศบาลตำบลตาดทอง. (2568). กระดูกไก่ดำ. สืบค้นจาก https://www.thadthong.go.th/rspg-8/item/857-2020-11-24-02-55-30
ดร.วุฒิ วุฒิธรรมเวช. (2558). กระดูกไก่ดำ. ใน ดร.วุฒิ วุฒิธรรมเวช (บ.ก.), ย่อเภสัชกรรมไทยและสรรพคุณสมุนไพร (พิมพ์ครั้งที่ 4, น. 77). บริษัท ศิลป์สยามบรรจุภัณฑ์และการพิมพ์ จำกัด.
อำพล บุญเพียร, ธิดารัตน์ แจ่มปรีชา, และ นิภาพร แสนสุรินทร์. (2562). ผลของการนวดด้วยน้ำมันกระดูกไก่ดำ (Justicia gendarussa Burm.f) และน้ำมันไพล (Zingiber cassumunar Roxb.) ต่ออาการปวดคอ บ่า ไหล่จากกลุ่มอาการออฟฟิศซินโดรม. วารสารการแพทย์แผนไทยและการแพทย์ทางเลือก, 17(3), 450–462. สืบค้นจาก https://he01.tci-thaijo.org/index.php/JTTAM/article/view/186333
สุภาภรณ์ ปิติพร, ณัฐดนัย มุสิกวงศ์, ศักดิ์สิทธิ์ จิตรกฤษฏากุล, อัญชิสา กัทลี, ธนพงศ์ เพ็งผล และผกากรอง ขวัญข้าว. (2565). ประสิทธิศักย์และความปลอดภัยของสเปรย์ผสมสมุนไพรกระดูกไก่ดำเปรียบเทียบกับไดโคลฟีแนกสเปรย์ในการรักษาการบาดเจ็บของเนื้อเยื่อ. วารสารการแพทย์แผนไทยและการแพทย์ทางเลือก, 20(2), 223–234.
Kumar, K. S., Sabu, V., Sindhu, G., Rauf, A. A., & Helen, A. (2018). Isolation, identification and characterization of apigenin from Justicia gendarussa and its anti-inflammatory activity. International Immunopharmacology, 59, 157–167. https://doi.org/10.1016/j.intimp.2018.04.004
Raghu, M. G., & Agrawal, P. (2016). The isolation and structural determination of flavonoids from Justicia gendarussa. IOSR Journal of Pharmacy and Biological Sciences, 11(6), 73–79.
Shamili, G., & Santhi, G. (2018). Identification and characterization of bioactive compounds of leaves of Justicia gendarussa Burm. f. International Journal of Scientific Research in Biological Sciences.
Surwase, U. S., & Patil, S. M. (2021). In vivo and in vitro anti-oxidant activity of ethanolic extraction of Justicia gendarussa Burm leaves. Journal of Pharmaceutical Research International, 33(60B), 2922–2931. https://doi.org/10.9734/jpri/2021/v33i60B34961